RNA Details
Disease Name
nephritis interstitia
Tissue
kidney
RNA Symbol
Hotair
RNA ID
RNA Type
lncrna
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
NA
Target
NOTCH1
Pathway
NOTCH SIGNALING PATHWAY
PubMed ID
Title
Paeonol reverses promoting effect of the HOTAIR/miR-124/Notch1 axis on renal interstitial fibrosis in a rat model
Year
2019
Function
"The contributory effect of lncrna hotair on renal interstitial fibrosis by activating the notch1/jagged1 signaling pathway via inhibition of miR-124, whereas administration of PAE can alleviate the effects of hotair on renal interstitial fibrosis."